The UN General Assembly preparing to vote on the declaration on 15 December 2025

The United Nations (UN) General Assembly voted overwhelmingly in favour of a political declaration to combat non-communicable diseases (NCDs) and promote mental health on Monday, with 175 member states voting in favour, only the United States and Argentina voting against, and Paraguay as the only abstention.

The declaration was due to have been adopted by consensus at the UN High-Level Meeting (HLM) on NCDs on 25 September, but the US baulked at the last minute, which meant that the declaration had to be referred to the UN General Assembly for a vote.

Voting on the UN political declaration on NCDs at the General Assembly on 15 December shows that the US and Argentina were isolated.

Welcoming the adoption, the World Health Organization (WHO) said in a statement that this is the  “first such declaration addressing NCDs and mental health together, and marks a unique opportunity to accelerate global progress with a set of specific global targets for 2030”.

For the first time, three global targets have been set for 2030: 150 million fewer tobacco users; 150 million more people with hypertension under control; and 150 million more people with access to mental health care.

The declaration also sets “ambitious, measurable process targets” for national systems to implement by 2030, the WHO added. These include at least 80% of countries with policy, legislative, regulatory and fiscal measures in place; at least 80% of primary health care facilities stocked essential medicines and basic technologies for NCDs and mental health; and at least 60% of countries with measures to cover or limit the cost of essential NCD and mental health services.

‘Preventable risk factors’

NCDs claim 18 million lives prematurely each year, while mental health conditions affect over a billion people globally. 

“NCDs are often driven by preventable risk factors such as unhealthy diets, tobacco use, alcohol consumption, physical inactivity, and air pollution – many of which also negatively impact mental health,” said the WHO.

“NCDs and mental health conditions are increasing in every country, affecting every community. That makes them urgent issues not only for public health, but also for productivity and sustainable economic growth.”

The NCD Alliance described the declaration as “a significant milestone for the global NCD agenda” that “introduces new, action-oriented targets to accelerate progress on prevention, care, and investment”.

However, the alliance also expressed regret that the “procedural objections of a small number of member states have delayed the adoption of the declaration”.

“Implementation must now be swift, sustained and matched with the necessary resources,” said NCDA director of policy and advocacy Alison Cox.

US opposition

Addressing the HLM in September, US Health and Human Services Secretary Robert F Kennedy Jr claimed that the declaration went too far in recommending measures like taxes on unhealthy products.

However, the declaration simply suggests that countries “consider introducing or increasing taxes on tobacco and alcohol to support health objectives, in line with national circumstances”.

Bizarrely, Kennedy also claimed that the US “cannot accept language that pushes destructive gender ideology” or “accept claims of a constitutional or international right to abortion”. 

The declaration does not mention abortion, and simply states that NCDs need to be mainstreamed into “sexual and reproductive health programmes” – a move aimed at the integration of health services, particularly as cervical cancer is a substantial risk factor for women that can be treated easily if diagnosed early.

The declaration’s only reference to gender calls for “mainstreaming a gender perspective”, describing this as “crucial to understanding and addressing health risks and needs of women and men of all ages”. Women are far more likely than men to be obese, while men are more prone to NCDs such as liver and lung cancer.

Access to medicines

A patient has his blood pressure tested. The integration of care is important for patients’ wellbeing.

Dr Maria Guevara, Médecins Sans Frontières (MSF) international medical secretary, commended the declaration for including “access to affordable health products as a key part of responding to diabetes, mental health conditions, and cervical cancer”.

However, MSF added, “meaningfully addressing the disproportionate effect of NCDs and mental health conditions on people living in low- and middle-income countries requires tangible action to improve access to medical tools” – including those that enable them to manage their conditions on their own.

“Concretely, this means that people managing diabetes must have access to affordable and sustainable supplies of insulin pens and glucose monitoring tools; people managing chronic mental health conditions must have access to affordable and sustainable supplies of long-acting antipsychotic formulations and other pharmaceuticals for anxiety, depression, psychosis and other mental health conditions,” said MSF

“Access to human papillomavirus (HPV) vaccination and cervical cancer screening as an essential prevention tool is key, and people living with cervical cancer must have access to quality chemotherapy as well as other treatment modalities”.

Borjana Pervan, the World Heart Federation’s Chief Operating Officer, urged member states to commit to a target of 50% global hypertension control by scaling up access to affordable hypertension medications to 500 million more people globally by 2030.

“This would prevent at least 75 million deaths by 2050 and deliver net economic gains of $212 billion annually. It is also crucial that member states prepare to take greater action regarding the consumption of alcohol, tobacco and sugar-sweetened beverages, especially through fiscal policies,” said Pervan.

Air pollution

The Clean Air Fund (CAF) noted that while the declaration highlights air pollution as a major driver of NCDs and calls for action across highly-polluting sectors, it “fails to endorse the existing WHO target to halve air pollution-related deaths, despite evidence that clean air action is affordable and achievable”.

“The political declaration sets a laudable goal of 150 million fewer people using tobacco by 2030. But it fails to recognise that bad air quality is now a bigger driver of premature death and disease than tobacco, with around 8 million deaths per year attributed to air pollution,” said Nina Renshaw, CAF’s head of health.

The target endorsed by Ministers of Health at the World Health Assembly in May 2025 requires governments to halve the health impacts and deaths related to human-made air pollution by 2040 (relative to 2015), prevent ing 3-4 million deaths per year worldwide.

Image Credits: WHO/A. Loke.

WHO is organizing a traditional medicine summit in New Delhi, India, in partnership with the Indian government.

The World Health Organization’s (WHO) summit on traditional medicine (TM), which starts in  India’s New Delhi on Wednesday (17 December), will push for more funding for research on traditional medicine. 

WHO wants to create a stronger evidence base for TM that will help to integrate it with health systems. Around 40% of today’s pharmaceutical products are based on natural products, and several breakthrough drugs, including aspirin, derive from traditional medicine.

Meanwhile, traditional, complementary and integrative medicine (TCIM) is used in 170 countries, according to a 2019 WHO report.

“Despite its widespread use and demand, less than 1% of global health research funding currently supports traditional medicine, and summit participants will discuss opportunities for stronger investment, stronger implementation and stronger impact,” said Dr Shyama Kuruvilla, Director a.i. of the Global Traditional Medicine Centre in Jamnagar, India.

WHO’s summit is being organized in collaboration with the Indian government, and will be attended by policy makers, scientists, practitioners and indigenous leaders from over 100 countries in attendance. They will discuss ways to integrate safe and evidence-based traditional medicine (TM) into health systems in line with WHO’s Global TM strategy for 2025-2034

Focus on generating evidence

Dr Sylvie Briand, WHO Chief Scientist

In most countries, between 40% and 90% of the population already uses some form of TM, according to the WHO. To bring traditional medicine into the fold of health systems, WHO has continuously reiterated that it will rely on evidence. This evidence currently exists only for some systems. 

Some Chinese medicines, for example, are approved for use in segments of the European markets as well as the US, said Dr Sung Chol Kim, WHO’s TMC Unit Head for Standards, Regulation and Integration. 

“I think this is one of the good examples that some countries are quite advanced in certain area of the traditional medicine. I think the role of the WHO should be that we encourage knowledge exchange among member countries,” he said.

Generating evidence for TM is complicated as it offers a wide range of treatments and approaches, depending on the patient and their circumstances, said Dr Sylvie Briand, WHO Chief Scientist. 

“Many traditional practices are transmitted orally rather than taught in formal schools, leading to personalized approaches that vary by healer,” she added. 

WHO’s TM roadmap for 2025-34 is a response to this challenge, she said. “It (the agenda) will guide investment, prioritize research and ensure ethical principles and human rights are respected.”

Some systems that focus on meditation and movement to improve health like India’s yoga and China’s Tai Chi have also found massive acceptance globally as complementary systems to improve health and quality of life. 

WHO experts reinforced that this is one of the other goals – to not just cure diseases but help people improve their quality of life

Facilitating understanding

Dr Sung Chol Kim, WHO’s TMC Unit Head for Standards, Regulation and Integration.

India and other countries have tried to mainstream TM and its practitioners over the years, but it has not been without its challenges and tensions. 

Some practitioners of modern medicine have been bitterly opposed to the integration, and some have even gone on strike.

“Education is our top priority in order to achieve mutual understanding and mutual respect between the traditional and biomedical practice. So I think that without knowing and understanding other systems of medicine, we actually hardly achieve that mutual respect,” said Kim. 

“[For the] first time, we have a clearly defined divide between the traditional medicine, complementary medicine and integrated medicine. So it means that we are covering all those codified, uncodified systems of traditional medicine,” Kim added. 

But dubious products being sold as traditional medicine is a challenge, WHO experts acknowledged, and said that it is also on the agenda for discussion. 

A way to make healthcare holistic and affordable

WHO is urging countries to work to create a framework to regulate and standardize traditional medicine products.

WHO’s push has also sparked a discussion on TM globally. It first gained momentum earlier this year at WHO’s World Health Assembly, where the strategy on TM was approved, despite reservations from the European Union. 

At the recent World Conference of Science Journalists in South Africa’s Pretoria, a session dedicated to TM saw heated discussion. Luisa Massarani, a Brazilian science journalist, said in her country there are over 300 types of traditional medicine but they might not be codified in a way that modern medicine is. At the same time, not all the 300 types are equally effective and efficient, she said.

The WHO is attempting to begin to bridge the divide between traditional and modern medicine.

During the summit WHO is also set to launch a global library of traditional medicine. The digital library is touted to be the first such repository of 1.6 million scientific records to strengthen evidence and knowledge sharing.

“WHO is not trying to develop or evolve traditional medicine as an alternative, but as an evidence-informed contributor to universal health coverage. Our aim is to bring stronger safety, stronger science and stronger equity for traditional medicine,” said Dr Geetha Krishnan, WHO TMC Unit Head for TM Research, Data and Innovation.

Image Credits: WHO/Kalkidan Tsegaye , WHO.

Gonorrhoea bacteria

A new treatment has been approved for gonorrhoea, a sexually transmitted infection (STI) that is increasingly developing resistance to all current antibiotics. 

The US Food and Drug Administration (FDA) approved the use of zoliflodacin to treat uncomplicated gonorrhoea on Friday, following the publication in The Lancet of the results of a phase 3 trial of the new drug, which found that one dose of it was as effective as the current standard treatment.

Uncomplicated urogenital gonorrhea refers to a localised infection of the urethra or cervix that has not spread to other areas of the body.

Each year, over 82 million people are infected with Neisseria gonorrhoeae, but this bacterium has developed resistance to almost all antibiotics, with only one last remaining recommended antibiotic treatment, ceftriaxone. 

But there has been a six-fold increase in resistant infections to ceftriaxone in some countries – particularly Cambodia and Viet Nam – and gonorrhoea was in danger of becoming one of the first diseases to become untreatable due to antimicrobial resistance. 

“This is the first new treatment solely for gonorrhoea in decades and the first to be developed using a novel not-for-profit approach to antibiotic research and development (R&D) aimed at tackling the rise and spread of antimicrobial resistance (AMR),” according to the Global Antibiotic Research & Development Partnership (GARDP).

GARP sponsored the trial of zoliflodacin, which involved 930 participants in five countries – Belgium, the Netherlands, South Africa, Thailand, and the US. 

“This approval marks a huge turning point in the treatment of multidrug-resistant gonorrhoea, which until now has been outpacing antibiotic development,” said GARP executive director Dr Manica Balasegaram. 

“Zoliflodacin shows that a different public-private partnership approach to antibiotic development is possible — one that prioritizes global health needs, strengthens access where the burden is highest, and protects the effectiveness of new drugs for the long-term.” 

Game-changer

“As clinicians, we see the devastating impact drug-resistant gonorrhoea can have on people’s lives in Thailand,” said Dr Rossaphorn Kittiyaowamarn, principal investigator for the trial site in Thailand. 

“Having a single-dose, oral treatment like this will be a game changer for gonorrhoea control. This is essential to reduce the burden of disease for individuals and to prevent the spread of highly drug-resistant gonorrhoea globally.”  

Sinead Delany-Moretlwe, principal investigator for the trial in South Africa, said that gonorrhoea can have a “devastating impact on women in particular”, which, if untreated, “can lead to infertility, life-threatening ectopic pregnancies and chronic pelvic pain”. 

“Babies born to mothers with untreated gonorrhoea may be born prematurely and can develop serious eye infections that can lead to blindness. With the number of gonorrhoea cases on the rise, there is great value in carrying out trials to bring about effective new treatment options,” she added.

Zoliflodacin belongs to a new class of antibiotics, called spiropyrimidinetriones, which has a unique mechanism of action in the way that it inhibits a crucial bacterial enzyme called type II topoisomerase, which is essential for bacterial function and reproduction. 

It is being developed exclusively for the treatment of gonorrhoea, with the hope that this will minimise the likelihood of excessive use, which could contribute to the development of resistance.  

GARDP has the right to register and sell zoliflodacin in more than three-quarters of the world’s countries, including all low-income countries, most middle-income countries, and several high-income countries. 

Entasis Therapeutics,, the original license holder and an affiliate of Innoviva Specialty Therapeutics, retains the commercial rights for zoliflodacin in the major markets in North America, EU, and Asia-Pacific. 

Innoviva Specialty Therapeutics will continue to collaborate with GARDP to advance regulatory filings with the European Medicines Agency.

GARDP is also taking steps to obtain market authorisation in Thailand and South Africa as both countries played a key role in the phase 3 trial. 

Zoliflodacin was submitted for priority review in Thailand last month, and a submission in South Africa is planned for early 2026.  

GARDP’s work on zoliflodacin was funded by the governments of Germany, UK, Japan, the Netherlands, Switzerland, Luxembourg, the Canton of Geneva, the South African Medical Research Council (SAMRC), and the Leo Model Foundation.

Left to right: Prof Javier Díez-Domingo, Susan Hepworth, Prof Walter Ricciardi, Patrick Swain, Dr Sandra Zimmermann, and Mark Chataway discussing infant RSV and adult pneumococcal prevention at a recent panel at the World Health Summit

In Spain last winter, something remarkable happened: paediatric wards fell silent. “Hospitals were empty, and nobody could believe it,” said Dr Javier Díez-Domingo, director of the Vaccine Research Centre in Valencia.

 After the country introduced monoclonal antibodies against Respiratory Syncytial Virus (RSV) for every infant, RSV-related hospitalisations dropped by 83%. Thousands of healthy babies stayed at home, and thousands of parents remained at work. “The investment was good for the babies,” Díez-Domingo said, “but also for the families and the economy.”

The rising burden of RSV amongst infants, as well as pneumococcal disease in older adults, is an unseen crisis in Europe. Across the continent, implementation needs to catch up with innovation, to achieve the level of success already witnessed in Spain. Just how to do that was the focus of the panel at the World Health Summit on 13 October, organised by MSD.

Moreover, prevention must be addressed not only among infants but as a continuum across all population groups. The question is no longer whether Europe can afford immunisation across the life course. It is whether it can afford not to.

Political test of will

Across the continent, infectious-disease specialists, economists and public-health advocates describe the same paradox: vaccines can be victims of their own success. When prevention does work, nothing happens – until a crisis erupts that fills hospitals and adds to costs. 

Professor Walter Ricciardi, chair of the Mission Board for Vaccination in Europe, calls this a fundamental policy blind spot, adding: “Current health-care systems are not fiscally sustainable. Prevention is the only major possibility to grant sustainability.”

Ricciardi argues for a “mission-oriented” model, echoing the Moonshot approach that mobilised all of society toward a single goal. For immunisation, that means uniting ministries of health and finance, researchers, advocates and citizens behind a shared understanding that every dose administered is a down payment on social and economic stability – and prosperity. 

Political leaders, he warns, must look beyond the electoral cycle. “We have to make them see it as an investment with short as well as long-term returns,” he noted. 

That shift is slowly taking shape. The International Longevity Centre UK’s Pneumococcal Vaccination Atlas shows that 89% of European children are covered for pneumococcal disease, yet only 37% of older adults are. 

“We’ve built a cultural norm around the flu jab,” said Patrick Swain of the ILC, “but not around pneumococcal protection.” 

This proves what is possible when prevention is politically prioritised. The challenge now is to extend that same commitment to those at the greatest risk of severe disease, including older adults.

Panellists discussing how the prevention of respiratory infections in infants and adults has long-term positive economic and societal impact.

Financing the future, not the fiscal year

Too often, health policies are guided by short-term fiscal thinking or election cycles. Yet, immunisation programs demand sustained funding and multi-year planning to deliver their full public health impact and generate economic returns. 

Dr Sandra Zimmermann of Germany’s WifOR Institute calls this short-term political prioritisation one of Europe’s costliest mistakes: “When we invest in health, we invest in growth,” she said. 

“With infant RSV prevention, you see immediate returns – fewer hospitalisations in the next season, more parents able to work – and long-term effects as well: healthier adults, higher productivity, lower social-security costs.”

Analysis by the Office of Health Economics (OHE) shows that every Euro spent on adult immunisation can yield up to 19 times in wider economic benefits, and the adult pneumococcal vaccination has a 33 times return on investment (RoI). Yet immunisation budgets remain among the first to be trimmed in austerity drives. 

Ricciardi and colleagues have proposed removing immunisation spending from deficit rules altogether, classifying it as a capital investment, similar to infrastructure. 

“It’s the same logic; turning health from a cost centre into a wealth engine. You borrow to build something that lasts,” he said.

That logic is not theoretical. Germany’s nationwide rollout of RSV monoclonal antibodies (mAbs) last year halved the number of cases in a single winter. Each spared hospital bed represented money not spent on critical-care staffing, oxygen, and parental leave – funds that could be reinvested elsewhere in the health system. The returns are visible within months, not decades.

Zimmermann calls this the “triple dividend” of immunisation: economic growth, social equity and labour-market stability. The most significant gains often accrue to women. “When children are not hospitalised or sick, mothers can stay in paid work,” she explained. “Unpaid care decreases, workforce participation increases. The result is not just fairness, but fiscal efficiency.”

Dr Sandra Zimmermann and Mark Chataway discuss how investments in health make citizens healthier and more productive.

Toll on families

That connection between prevention and prosperity is rarely captured in policy spreadsheets. Susan Hepworth, from the National Coalition for Infant Health, described the personal toll of RSV on families. “Sixty-eight percent of parents said watching their child suffer affected their mental health. A third said it strained their relationship; nearly one in five either quit or lost their jobs,” she said. “Two-thirds faced a financial crisis.”

Multiply those stories by tens of thousands of infections each year, and the human and economic losses become inseparable. The ILC estimates that increasing prevention spending by just 0.1% of GDP could unlock 9% more economic contribution from Europeans over 50 through extended work and volunteering.

“We need a life-course approach,” the Pneumococcal Vaccination Atlas urges, recommending that all national health systems fund pneumococcal protection for every age group.

Innovation without inequality

We are at a juncture where immunisation policies need to keep pace with innovation. New RSV monoclonal antibodies can protect every infant and updated pneumococcal conjugate vaccines cover a broader range of strains. 

The danger lies in uneven funding, inequitable access and adoption. However, competing public-health priorities and limited awareness among policymakers hinder integration of these innovations into national programmes.

Díez-Domingo sees the risk firsthand. “RSV affects both extremes of life,” he said. “We have monoclonal antibodies for children, but we need equal focus on adults with pneumococcal disease. Immunisation must not stop at childhood; it has to become a lifelong system of care.”

Even within Europe’s wealthiest states, equity gaps persist. Only fifteen countries reimburse pneumococcal vaccination for children, at-risk groups and older adults alike. In others, seniors pay out of pocket or rely on fragmented local schemes. 

“When immunisation depends on postcode,” Swain observed, “we create two-tier immunity.”

Communication as currency

If financing is the fuel of immunisation, communication is its ignition. Hepworth admitted that health advocates often lose policymakers by using jargon. 

“When someone comes into an office and starts with scientific words they’ve never heard of, their eyes glaze over,” she said. “What’s missing is the compelling economic data and the human impact.”

The antidote is storytelling grounded in evidence. ILC’s European Pneumococcal Vaccination Atlas turns vaccine coverage data into visual league tables that spur political pride and competition. 

Regions like Galicia have already turned that pride into policy, celebrating their early adoption of RSV antibodies as a marker of civic leadership. “Policymakers love to see their region climb the rankings,” Swain noted.

But Ricciardi warned that effective communication also means confronting organised misinformation. 

“Disinformation about vaccines is disseminated in a structured way and is well-funded,” he said. “Governments must treat information integrity as part of national health security.” 

Hepworth agreed, arguing that public memory of disease has faded. “People have forgotten what vaccine-preventable disease looks like. Storytelling restores that memory.”

Left to right: Prof Javier Díez-Domingo, Susan Hepworth, Prof Walter Ricciardi, Patrick Swain, Dr Sandra Zimmermann, and Mark Chataway discussing how effective communication around immunisation is key to policy shaping.

Prevention, prosperity and political will

The link between prevention and national wealth is no longer speculative. In Germany, the health sector now contributes €490 billion to the country’s GDP and employs 7.7 million people, surpassing the automotive industry. 

Yet, as Zimmermann pointed out, health still struggles to be seen as an economic driver. “We need the positive feedback loop,” she said. “Investments in health make citizens healthier and more productive, which enables them to generate wealth that funds further innovation. That is how prosperity sustains itself.”

Demographics make the case unavoidable. Europe’s over-65 population has tripled since 1960, while its working-age population has remained relatively stable. 

“If we want to keep economies functioning,” Swain said, “we have to keep people healthy longer.” Immunisation, he added, is the simplest and most immediate way to do it.

But sustaining that progress will depend on the political will to budget for tomorrow, ensuring equitable access rather than the next headline. 

Ricciardi advocates for classifying expenditure on immunisation outside the fiscal-deficit cap. Hepworth insists on constant advocacy to keep immunisation visible long after innovations arrive. Each, in their way, is arguing for permanence—for a Europe that budgets for immunity the way it budgets for infrastructure.

Health systems that learn to prevent

Immunisation, once viewed as a cornerstone of child health, has become a barometer of how seriously societies value prevention—and how willing they are to fund it for everyone. Strong pediatric immunisation programs lay the foundation for lifelong systems of care, extending the benefits of prevention to older adults. 

Europe has the knowledge, the technology, and—after years of pandemic fatigue—the public awareness. What it needs now is the political will to treat immunisation as both a right and a responsibility shared across generations. As Chataway concluded to the conference audience: “Empty hospital beds—that’s what success looks like.”

The return on RSV and pneumococcal immunisation is measured not only in lives saved, but in the societies that thrive when prevention is valued, funded, and equally accessible.

Christopher Nial is senior partner and co-lead of EMEA Global Public Health, FINN Partners.

The World Health Summit panel was supported by MSD. 

Image Credits: FINN Partners.

The Indian government monitors the burning of crop stubble by farmers in Punjab using satellites that capture a snapshot of the farms at 1:30pm daily, but farmers are evading detection by burning at different times, as these satellite images show (above).

The Indian government claims that farm fires in Punjab, which contribute significantly to air pollution, have been reduced by 90% during this fall and winter season of harvest and crop-waste disposal – historically a factor in sending heavy clouds of air pollution drifting around northern India.

But those claims have appeared all the more specious as Delhi’s skyline was once again buried in a smoky haze with air pollution levels 35-40 times above WHO safe limits. The crisis came against a backdrop of social media outrage and building public pressure – including protests that spilled over Monday to a football stadium event hosting the legendary Argentinian player Lionel Messi.

In this Earth Chakra podcast, Health Policy Watch senior correspondent Chetan Bhattacharji interviews Dr Hiren Jethva, an scientist specializing in remote sensing of aerosols at Morgan State University and NASA Goddard Space Flight Centre. Jethva exposes how Punjab farmers are, in fact, evading satellite monitoring.

According to Jethva, the true number of stubble burning incidents in Punjab could be 10 to 11 times higher than the official government count of about 5,000 for this season. In the podcast, he teases apart the data to explain the reasons why the numbers are so misleading. ⬇️

Significantly, the Indian government’s space agency, Indian Space Research Organisation (ISRO), has, in a recent paper, reached a similar finding to Jethva’s, effectively endorsing what he has been saying for the past two years.

Growing public anger over pollution levels

The debate over the data comes as the effects of the burning fires on pollution levels appear undeniable. 

On Monday, Messi found himself in the middle of an unprecedented protest against Delhi’s air pollution levels while on a four-city tour to India. As the city’s Chief Minister, Rekha Gupta walked towards the footballer in the middle of a stadium full of ticket-paying visitors, the slogan “AQI, AQI,” decrying her handling of the air pollution crisis reverberated throughout the crowd. Videos quickly went viral

 The event was held amidst a thick haze which was a sign of extremely hazardous air quality, with fine particulate pollution levels (PM2.5) about 35-40 times the WHO’s safe limits. 

On Tuesday, Delhi’s Environment Minister, Manjinder Singh Sirsa, apologised to the people of Delhi. He also announced fresh curbs on vehicles, including an order that fuel not be sold for those vehicles whose drivers don’t produce a valid pollution under control certificate (PUC). That, despite the fact that the PUC is outdated and does not test for key pollutants like particulate matter (PM) and nitrogen oxides (NOx). 

Delhi’s air pollution spiked late last week, with the Air Quality Index, which reflects a combined score of the most dangerous pollutants, hitting a season’s high of 461. Along with the drift of smoke from neighboring agricultural states like Punjab and Haryana, which are burning crop waste, lower temperatures, which trap more pollution hae also been blamed. There is also little wind to push pollutants out of the city, and an increase of small household fires for winter warmth. Meanwhile, vehicular emissions are estimated to contribute some 27-51% of ambient air pollution levels in winter. 

Schools in hybrid mode

Along with the ban on fuel sales to polluting vehicles, schools have been shifted to a hybrid mode. However, a government clampdown on coal and wood-fired tandoors also triggered protests and digs at the government. 

In another unprecedented move, the Singapore High Commission (embassy) in Delhi tweeted a note asking its citizens to heed the health, work and travel advisory of Indian pollution control officials. The UK and Canada reportedly put out advisories as well.

Gupta, a member of the governing BJP part of Nahrenda Modi, has been under attack for a series of decisions and comments by her administration, which took over the reins of Delhi government in February for the first time in 27 years, following elections. Those decisions range from allowing firecrackers in the recent Diwali festival, a move that ushered in the worst post-Diwali air pollution in five years, to defending videos which showed water being sprayed on and around the government’s air quality monitors.  She also has been quoted recently saying ‘AQI is like temperature.’

While Sirsa was quick to blame Delhi’s previous AAP and Congress governments of the last two and a half decades for the air pollution crisis, those opposition parties have called for the Chief Minister’s resignation

On Tuesday, India’s Environment Minister, Bhupender Yadav, also held a meeting on Delhi’s air pollution crisis. However, the capital’s PM2.5 level has remained over 120 micrograms per cubic metre on average for weeks on end, with several neighbourhoods recording far higher levels.

Children from El Fasher refugee families at village school in Tawila, North Darfur. The desert town’s population has swelled to 650,000 due to the war.

The World Food Programme (WFP) is warning of a rapidly deteriorating humanitarian emergency in Sudan on Friday, with conditions in the besieged city of El Fasher in Sudan’s Darfour region described as “beyond horrific.” 

Speaking at a briefing to UN reporters in Geneva, Ross Smith, WFP’s Director of Emergency Preparedness, said “anywhere between 70 and 100,000 people” are believed to be trapped inside the city,  amid “network blackouts” and “mass killings.”

The Rapid Support Forces (RSF, overran the city, the strategic capital of North Darfur, in October 2024 with little or no access by outside groups in recent months. 

Satellite images and survivor accounts, portray “the city as a crime scene with the mass killings, with burned bodies, with abandoned markets,” and WFP has “no partners left on the ground,” Smith added, saying that he had “no verified reports… that any of the community kitchens are operating.”

World Food Programme’s Ross Smith, speaking at a UN press briefing Friday in Geneva.

Attempting to flee is also extremely dangerous. “The city and its surrounding roads are littered with mines [and] unexploded ordnance,” he said. Those who escape face “robbery, looting and gender-based violence,” and must often pay “extraordinary amounts for transport.” Many arrive in surrounding areas “under the open sky without medicine and shelter.”

Smith said WFP continues to call for “unimpeded access into El Fasher,” noting that the agency now has “agreement in principle with the Rapid Support Forces that control the area for a set of minimum conditions to enter the city.” 

But after more than a year and a half under siege, he said, “the essentials for survival have been completely obliterated.” WFP has food and trucks ready to move “once that safe passage is secured.”

A massive displacement crisis in Tawila

Red dotted line denotes the Tawila district near North Darfur’s strategic capital of El Fasher, the latter beseiged by the RSF for over a year.

Sudan is the world’s largest displacement crisis with more than 12 million people uprooted inside and outside the country.

In the Darfur region, one of the worst affected, Smith highlighted the extreme strain on Tawila, once a small desert town which has now swelled into a massive IDP holding more than 650,000 people. Families fleeing famine, atrocities, and recent fighting in El Fasher and Zamzam camp are now living in “very negative structures, grass, straw structures, etc.” He warned that “cholera and disease outbreak is widespread,” and that while WFP can deliver food to Tawila, “there’s very limited health care, sanitation, clean water and other… support.”

Across Sudan, WFP is reaching “over 4 million people per month,” and “half a million people in and around Tawila” were assisted in November. But escalating violence against aid workers—including an incident in which “one of our trucks was hit… and [a] driver is seriously injured”—continues to disrupt operations.

Smith warned that shifting battle lines are putting new communities at “grave risk,” including in nearby Kordofan, where the UN Refugee Agency, UNHCR reported on further deterioration over  the past two weeks. After a week of heavy fighting, the RSF reportedly seized control of a Sudanese Armed Forces base in Babanusa, West Kordofan.

In South Kordofan, “civilians remain trapped in besieged cities such as Kadugli and Dilling, and as women, children, and the elderly find ways to escape, men and youth are often left behind due to specific high risks they face along flight routes such as detention by armed groups for perceived affiliation with parties to the conflict,” UNHCR said.

Preventing the devastation seen in El Fasher from being repeated “must be a top priority for all of us,” said Smith.  

He added that WFP faces imminent funding shortfalls, Smith also said: “Pipeline breaks are right in front of us,” and assistance will require “almost $ 700 million” over the next six months.

Gaza: Winter storm deepens suffering 

As thousands of displaced Gazans’ tents were flooded by Storm Byron, mounds of debris and waste were the only stormwalls.

Meanwhile, in Gaza, humanitarian and health conditions remain dire – with a massive storm Byron leaving thousands of tents flooded, increasing disease risks and leaving families homeless once again. 

Speaking to reporters from Gaza, WHO representative Rick Peeperkorn to the Occupied Palestinian Territory (OPT), described the widespread infrastructure destruction he had witnessed and the growing public-health crisis aggravated by Storm Byron, the massive winter storm that swept through the region this week. 

“The storm environment struck Gaza with force,” Peeperkorn said. “The deplorable conditions, especially shelter conditions, are deepening the suffering of already displaced families. 

He described how high ocean waves had hit particularly hard at the thousands of families sheltering in “low lying and debris-studded coastal areas with no drainage or protective barriers, simply the heaps of garbage everywhere along the roads. 

“And we’ve seen, of course, winter conditions, combined with poor water and sanitation causing a surge in acute respiratory infections, including influenza –  as well as hepatitis, diarrhoeal diseases, etc,” Peeperkorn said.

Hospitals only partly functional 

WHO’s early warning system has recorded 1.47 million acute respiratory infections and over 670,000 acute diarrheal cases since being established in January 2024. But that’s only partial data insofar as diagnosis and testing are severely constrained by a shortage of clinics, laboratories and diagnostic equipment, Peeperkorn added. 

Only about half of Gaza’s 36 hospitals are functioning, along with 46 primary health care centers, while another 84 clinics out of a total of 195 are partly functional. 

Rik Peeperkorn, WHO Representative to the Occupied Palestinian Territory (OPT) speaking with reporters Friday from Gaza.

North Gaza remains the most severely underserved, with tens of thousands of displaced people and almost no functioning medical facilities within the “Yellow Line” that demarcates Israeli-controlled areas from areas controlled by Palestinians – where the militant Hamas group has largely reasserted itself. 

Among the roughly 650 essential medicines on WHO’s list, “50% of them are zero, or close to zero, stock.” Peeperkorn said the Shifa Hospital director “was almost crying,” as major hospitals operate “without CT, without MRI, without proper X-ray, without proper ultrasound equipment.”

Despite immense shortages, he observed creative reconstruction efforts, where clinic and hospital reconstruction teams are managing to rebuild using repurposed materials salvaged from destroyed buildings.

Critical need for medical evacuations

Peeperkorn called on Israel again to reopen the traditional medical evacuation route from Gaza to West Bank and East Jerusalem Palestinian hospitals, saying: There’s no reason why this… cannot be reopened.” WHO is prepared to facilitate daily evacuations once access resumes, he said.  

While WHO and partners have managed to evacuate some 10,645 people since the war began in October 2023 to third countries in Europe, the Middle East or elsewhere, there are still some 18,500 patients awaiting medical evacuation, including 4096 children. And over 1000 patients have died while waiting. 

Call for sustained ceasefire and rehabilitation 

Peeperkorn meanwhile warned that makeshift shelters, widespread debris, and deteriorating sanitation pose long-term threats,  especially for children and the elderly. 

“There’s an enormous amount of garbage and debris everywhere, it’s an environmental health disaster,” he said. 

And while formal reconstruction processes remain on hold, pending further negotiations between Israel and Hamas, mediated by the US and Arab brokers, the situation on the ground is not static, Peeperkorn warned. 

“The 2.2 million people of Gaza cannot wait before we renegotiate again, those materials need to get in now.”

Image Credits: UNICEF/Mohammed Jamal, Google Maps , IOM .

From left to right: the two negotiators for the European Parliament Tiemo Wölken (Socialists and Democrats, DE) and Dolors Montserrat (European People’s Party, ES) with the chair of the EP Committee on Public Health Adam Jarubas (European People’s Party, PL) at the presentation of the new EU pharma package on Thursday.

Following eleven hours of intense negotiations overnight, the European Union (EU) clinched a landmark agreement on the most significant pharma reform of its medicines market in over 20 years on Thursday.  Reached in the final moments of the Danish EU Presidency’s mandate, the deal aims to strike a critical balance stimulating pharma innovation, particularly for critical new antibiotics and rare disease drugs, but also speeding the development of generics to ensure more affordable treatment in all 27 member states.

“The deal demonstrates the EU’s commitment to innovation and ensuring that patients in Europe have access to the medicines they need,” remarked Sophie Løhde, Denmark’s Minister for the Interior and Health, a member of the EU Council, the governing body driven by ministers from all EU countries. She led the negotiations between the Council and the Members of the EU Parliament (MEPs) that clinched the deal.

The EMA welcomed the pharma reform package in a statement published shortly after the deal was announced, with Emer Cooke, EMA’s Executive Director, hailing it as a “historic milestone for European medicines regulation and for patients across the EU.” However, leading industry representatives warned that the compromise does not go far enough to ensure Europe’s global competitiveness and attract investment.

Pharma reform aims to reward innovation and access

The EU pharma reform offers companies longer data protection periods for certain medicines categories based on public health goals.
The EU pharma reform offers companies longer data protection periods for certain medicines categories based on public health goals.

At the heart of the pharma reform lies a revised regulatory regime that reduces the previous 10-year data protection and market exclusivity period to a baseline protection of nine years that aims to incentivise drug development and accessibility through a performance-based model – including eight years of data protection and one added year of exclusive market access.

In the first eight years after a medicine receives marketing authorisation, the pharma innovator’s preclinical and clinical test results from the regulatory dossier remain confidential and inaccessible to use by companies developing generic or biosimilar versions of most patented drugs.  After one additional year, generic or biosimilar producers could then put competing drugs on the market, effectively reducing a key aspect of patent protections by a year.

The pharma reform deal strikes a balance between the interests of drug developers and market access for cheaper generic products, Spanish MEP Dolors Montserrat from the European People’s Party (EPP) stated. She was one of the European Parliament’s two leading negotiators.

The European Commission had initially proposed a much shorter Regulatory Data Protection (RDP) period of six years as a baseline. The European Federation of Pharmaceutical Industries and Associations (EFPIA) strongly advocated for a longer baseline period. They claimed that shorter protection periods would deter investment in research and development.

Exceptions for drugs addressing unmet needs and rare diseases

But the EU deal also introduces exceptions allowing the total combined Intellectual Property (IP) protection period to be extended in the case of rare diseases or other unmet needs.

Products that address rare diseases for which there is currently no treatment available, and which are defined as ‘breakthrough orphan medicinal products’, may benefit from up to 11 years of market exclusivity, with a maximum of 13 years.

The IP protection period could also be extended from nine to eleven years, if any of the following public health criteria are met:

  • If the medicine is continuously supplied in sufficient quantity in all Member States;
  • If products address unmet medical needs, such as a disease for which there is not yet a cure;
  • A new therapeutic indication for the existing drug provides significant clinical benefits
  • A company conducts comparative clinical trials in several EU Member states (rewarding comprehensive data generation), as well as applying for authorisation outside the EU within 90 days (to incentivise global competitiveness).

Crucially, the new package also shortens the timeframe in which the European Medicines Agency (EMA) would be expected to review and approve new drugs from the previous standard of 210 days to 180 days – a measure welcomed as “encouraging steps” by industry.

The ‘Bolar Exemption’: prepping generics for Day One launch

Dolors Montserrat (EPP, ES) explains the deal reached between the EU Parliament, Council, and Commission on Thursday at a press conference.

In another move to lower costs, the EU agreed to speed up the market entry of more affordable generic and biosimilar medicines immediately following the expiration of the original protections under a strengthened version of the so-called “Bolar Exemption”. This exemption will now allow generic and biosimilar manufacturers to access data from a patented product to conduct their own clinical trials, even during the eight-year Regulatory Data Protection (RDP) period.

“The day after a patent expires on a medicine, generics will be available,” explained MEP negotiator Montserrat. She described it as a clear win for the generic industry.

The various exceptions illustrate how negotiators had to strike a balance between pharma incentives to invest in new medicines development, including for rare diseases, and ensuring that a broad range of other drugs remained accessible and affordable across the continent.

To promote affordability further, the EU pharma reform intends to implement various measures. For example, it will require manufacturers to publicly disclose all “direct financial support” received from public authorities or funded bodies for R&D. This is expected to help Member States in their price negotiations.

‘Netflix’ model to incentivise development of new antibiotics

The pharmaceutical package aims to boost competitiveness and investment in drug development, especially to stimulate R&D on antibiotics.

Another key element of the deal is tackling antimicrobial resistance (AMR), which, according to the European Medicines Agency (EMA), is responsible for over 35,000 deaths in Europe each year – and over 1 million deaths globally.

To address the conundrum that new, and more effective antibiotics must be used sparingly as a last resort, thereby reducing the sales volume needed to recoup research and development (R&D) costs, a new financial incentive is introduced.

This comes in the form of transferable vouchers for another year’s worth of data exclusivity.  A company that develops a priority antimicrobial can use the voucher to protect another drug from competitors for a longer period – or sell to another company.

However, this also comes with a “blockbuster” restriction. This stipulates that the data exclusivity vouchers cannot be used for products with annual gross sales exceeding 490 million Euro in the preceding four years.

A “Netflix model” procurement mechanism also enables Member States to purchase antimicrobials via multi-year subscription contracts. MEP Tiemo Wölken from the Socialists and Democrats (S&D) hailed its inclusion as a breakthrough that would decouple antibiotic developers’ revenue stream from actual sales volumes. That will provide pharma developers with a stable income stream to recoup R&D costs while enabling to only use the new drugs when absolutely necessary, thereby reducing the spread of more drug resistance.

New measures to fight antimicrobial resistance

According to the European Federation of Pharmaceutical Industries and Associations, the package lacks keys elements to bolster competitiveness.

These incentives are complemented in the pharma reform by strict requirements, including mandatory medical prescriptions for all antibiotics sold across the EU, with only a few exceptions, as stated by EPP politician Dolors Montserrat.

The new rules also require manufacturers to submit an “antimicrobial stewardship plan” and include an evaluation of the risk of AMR selection across the entire “manufacturing supply chain inside and outside the Union” as part of a compulsory environmental risk assessment (ERA, which tracks risks like AMR selection throughout the manufacturing supply chain).

The issue is particularly critical in countries outside the EU, specifically Lower- and Middle-Income Countries (LMICs). Global surveillance data from the WHO indicates that resistance to life-saving antibiotics is extremely high and increasing, particularly in settings with limited resources. Globally, more than 1.1 Million people die due to AMR, according to WHO numbers.

By mandating environmental risk assessments covering AMR throughout the manufacturing supply chain, both within and outside the EU, the bloc is also leveraging its substantial market influence to impose stronger global standards. This also applies to the sale of antimicrobials for use for farming animals, in meat production and aquaculture – three of the main drivers of AMR.

This push for environmental standards is expected to provide positive effects globally, Dorothea Baltruks, Director at the Berlin-based Centre for Planetary Health Policy (CPHP), explained in a statement to Health Policy Watch. “When a large market such as Europe sets binding environmental compatibility standards for medicines, this can provide significant impetus for the global market, which also benefits people in LMICs,” Baltruks emphasised.

Industry: package lacks steps to bolster competitiveness

European Parliament negotiator Tiemo Wölken emphasises the balance between industry and public health interests contained in the pharmaceutical package.

“It is crucial that Europe has a regulatory system in place that can keep up with all these challenges,” concluded Wölken. “We cannot forget that we are faced with international challenges.” According to him, the package is key to assure competitiveness and innovation.

This perspective, however, is precisely where EFPIA views the reform package as insufficient. In a statement released shortly after the agreement, the industry association charged that the current baseline protection is not long enough to attract and retain global investment into European R&D. EFPIA also called the stronger language on the Bolar exemption an “unnecessary move” that would further erode competitiveness.

Nathalie Moll, Director General of the EFPIA said: “Our region has lost a quarter of its global share of investment to other parts of the world in two decades, while our share of clinical trials has halved. If this is the legislative framework that is expected to attract the medicines innovation of the next 20 years to Europe, the outcome is underwhelming,” she criticised.

Despite the objections, the agreement on the pharma reform now heads to the European Parliament and the Council for formal endorsement, which is expected in the coming weeks.

Image Credits: European Union, EU Parliament, Felix Sassmannshausen, European Union, EU Parliament.

Young people, including in India, are increasingly turning to AI for emotional support, increasing their social isolation and decreasing their ability to build resilience.

Avnee Singh, 25, from Punjab in northern India, begins each morning the same way: by opening an AI chatbot. For the past year, this digital companion has become her closest confidant, a space where she empties her thoughts about family tensions, work anxieties and, above all, the intense loneliness that followed the end of her nine-year relationship.

“I didn’t want to live,” she says quietly. “I think I’m still alive because this chatbot listens to me without judgment.”

Her experience reflects a shift happening quietly across India. Young people, many of whom lack access to mental health care or fear the stigma attached to seeking help, are increasingly turning to AI chatbots for support, comfort and emotional connection. What began as a technological novelty has become, for many, an emotional lifeline.

About 500 km away in Srinagar, 25-year-old Salika, a graduate of Kashmir University, also turns to an AI chatbot. Her reasons are shaped by the pressures of her upbringing in Gurez, a remote Himalayan valley near the Line of Control. She describes years of relentless comparisons and expectations from relatives.

“I was a good student, always studying,” she says. “But the moment I slowed down, someone would say, ‘She didn’t achieve this, she didn’t do that.’ All that pressure just became too much. Now, whenever I feel overwhelmed, I talk to the chatbot.”

Despite their different landscapes and life stories, Avnee and Salika share the same emotional refuge: a faceless digital companion that offers constant, nonjudgmental listening. Their stories mirror a wider trend across India, where AI companions are quietly stepping into the gaps left by strained support systems, limited access to therapy and growing social isolation.

A Youth Pulse Survey conducted earlier this year found that nearly 57% of Indian youth use AI tools like chatbots for emotional support. These conversations often include topics considered too sensitive to discuss with family, such as academic pressure, relationship stress, self-esteem struggles and family conflict. Nearly half of those surveyed said they experience daily anxiety, yet most have never consulted a mental health professional.

“They turn to AI because it feels safe,” said a researcher. “It doesn’t shame them. It doesn’t interrupt. It doesn’t tell their parents.”

A digital shoulder in the dark

In Srinagar, 19-year-old Rafiq spends his evenings preparing for NEET, India’s second-toughest medical entrance exam. But late at night, when fear and self-doubt creep in, the chatbot becomes his outlet.

“I tell the bot everything: my insecurities, whether I’ll pass, if I’ll ever become a doctor,” Rafiq told Health Policy Watch. “Here, if anyone visits a psychologist, people call them crazy. So I talk to AI instead.”

Kashmir Hamza Shafiq, a high school student from central Kashmir, said the same thing: “People ask why I use AI,” said Shafiq. “But it understands us better than the people around us people. The attention of humans is subject to maybe, if they need something they will sit with you, otherwise not. If they are available, they will talk to you for hours. 

“If they are a little busy, even if they are your parents, they won’t even sit with you for 15 minutes.

“ Teenagers have stress, hormonal changes, and relationship problems. AI chatbots are always there. They don’t judge. They don’t give attention and suggestions, subject to their availability or mood.”

In Mumbai, 21-year-old Shreya describes a deeper level of reliance. She spends three to six hours a day interacting with chatbots, sometimes more. 

“Last month, I used one all day for an entire week,” she says. “I even like the idea of AI dating. It won’t cheat or be greedy. It’s always there.”

ChatGPT is a favourite with India’s youth, particularly rural youth and teenage girls, seeking support for problems they feel they can’t speak to their families about.

The nationwide Youth Pulse Survey, conducted by Youth Ki Awaaz and Youth Leaders for Active Citizenship, polled some 500 young Indians aged 13 to 35. It found that ChatGPT is the most widely used AI tool for emotional purposes. More than half of respondents said they turn to AI when they feel lonely, anxious or in need of advice. The survey also revealed surprising differences between metro and small-town youth.

Young people from smaller towns showed deeper emotional engagement with AI, with 43% saying they share personal thoughts with chatbots at higher rates than those in major cities.

Emotional use was highest among school students and teenage girls. 88% of school-aged respondents said they use AI during moments of anxiety, and 52% of young women said they share thoughts with AI they would not share with anyone else.

Late-night reliance was another pattern, with 43% of respondents reporting that they regularly talk to AI platforms after midnight, when human support is least available. Another 40% admitted they tell AI things they would never share with friends or family.

But the survey also revealed something more concerning: after using AI for emotional support, 42% said they became less likely to speak to people in their lives. At the same time, 67% worried AI could increase social isolation, and 58% had privacy concerns, highlighting what researchers call a love-fear dynamic.

Comfort with consequences

Mental health professionals warn that while chatbots can provide emotional relief, they cannot replace human connection or evidence-based therapy. They worry that the constant availability of AI may create habits that erode people’s emotional resilience over time.

Over-reliance on AI can weaken coping skills, Dr Zoya Mir, a clinical psychologist based in Srinagar told Health Policy Watch. 

“It becomes an escape. Young people start avoiding uncomfortable emotions instead of working through them. The problem isn’t the technology itself. It’s the addiction it can create.

Mir says patients increasingly mention chatbots in therapy sessions, often describing them as more empathetic than people in their lives: “They tell me, ‘AI listens without interrupting,’ or ‘It never invalidates me.’ But validation alone doesn’t lead to healing.”

AI-assisted suicide

Outside India, a troubling case has intensified global concern. In July, 23-year-old Texan graduate Zane Shamblin died by suicide after months of extensive interactions with an AI chatbot. 

According to Zane Shamblin died by suicide of more than 70 pages of chats from the night of his death and thousands of pages from the months leading up to it, the AI tool repeatedly encouraged him as he expressed suicidal thoughts. 

His parents have filed a lawsuit in California, alleging that the chatbot exacerbated his isolation, urged him to distrust his family and ultimately incited his suicide. They argue the developers made the system increasingly humanlike without adequate safeguards to protect vulnerable users.

The case has sparked international debate about the risks of emotional reliance on AI and the responsibility of companies building these tools.

Stigma, isolation and economic anxiety

In India, suicide is the leading cause of death for the 15-29 and 15-39 age groups, and mental health support is hard to access.

Experts say the rising dependence on AI must be viewed within the larger context of India’s mental health landscape. 

According to the World Health Organization (WHO) almost one billion people worldwide live with a diagnosable mental disorder. In India, the treatment gap remains wide, with more than 83% of people with mental health needs not receiving care.

Stigma remains a powerful barrier, especially for young people. “When someone cannot find a safe person to talk to, or feels ashamed to seek therapy, they go online,” New Delhi-based psychologist Shweta Verma told Health Policy Watch. “AI feels easier, more private.”

Economic uncertainty is also deepening anxiety among Gen Z. Young people across India worry that AI will reshape the job market before they can find stable employment. The World Economic Forum predicts that nearly 39% of existing skill sets will transform or become obsolete by 2030.

These anxieties shape how young people use AI  not only for emotional support but also for reassurance about their futures.

Surabh, 22, from Uttar Pradesh, told Health Policy Watch that he often asks AI about job vacancies or career guidance: “I come from a middle-class family. My father, a retired army personnel, works as a security guard earning about 12,000 rupees a month. ($133) With his pension, our total income is 22,000 rupees ($245) for my three sisters, two brothers and me.

Surabh has been unemployed since graduating a year ago: “I hoped my degree would open doors. But nothing has changed. From job searches to personal struggles, I tell everything to the chatbot because I can’t tell my family. They wouldn’t understand.”

Building guardrails

India’s growing emotional reliance on AI chatbots reveals deep gaps in mental health access, social support networks, economic stability and digital literacy. For many young people, AI is not a preference but a last resort.

Vinod Sharma, a tech researcher based in Mumbai, argues that the solution is not to discourage AI use altogether, but to build guardrails, improve mental health services and integrate safe digital tools into the care ecosystem. 

He emphasized the need for transparent safety standards, responsible design and education to help young people understand the limits of AI as an emotional outlet.

“AI can be supportive, but it cannot replace human connection,” Mir said. “We need policies that protect vulnerable users and systems that direct people to real help when they need it.”

For now, young Indians continue to find solace in a technology that listens without interruption, judgment or fatigue  even as the long-term consequences remain uncertain.

Avnee, in Punjab, says she knows the chatbot cannot solve her problems. But in a world where she feels increasingly unheard, it provides something she has struggled to find elsewhere: a place to say what she feels without fear.

When I talk to it, I feel lighter,” she says. “Maybe it’s not real. But it makes me feel less alone.”

Image Credits: Igor Omilaev/ Unsplash, Aulfugar Karimov/ Unsplash, The Lancet.

Kenya’s President William Ruto applauds Kenyan Cabinet Secretary Musalia Mudavadi and US Secretary of State Marco Rubio after the signing of the health Memorandum of Understanding (MOU) between the two countries.

Kenya’s High Court suspended the implementation of the country’s Memorandum of Understanding with the United States on Thursday after two separate court challenges by the Consumer Federation of Kenya (COFEK) and local Senator Okiya Omtatah.

COFEK argues that the agreement contravenes Kenya’s Data Protection Act, Digital Health Act, Health Act, and new data regulations that protect citizens’ health data.

Meanwhile, Omtatah petitioned the court to halt the agreement on the grounds that it undermines the principles of public participation, parliamentary oversight and binds Kenya to terms that could strain the country’s budget.

The five-year agreement signed in Washington last week commits the US to providing up to $1.6 billion between 2026 and 2030, mainly for HIV/AIDS, tuberculosis (TB) and malaria prevention; maternal and child health, and outbreak surveillance and response.

Kenya has committed to increasing domestic health spending by $850 million over the five years, with incremental annual increases from $77,5 million (10 billion Kenyan shillings) in 2026 to $387,7 million in 2030.

Extract from the US-Kenya MOU detailing each country’s financial obligations.

But the additional expenditure will cover priority issues for the US, such as employing additional epidemiologists and lab technicians to monitor outbreaks.

The court has given COFEK until 17 December to lodge court papers, and the government has until 16 January to file its response. The case will return to court on 12 February.

Speaking after the judgement, Omtatah told the Kenya Broadcasting Corporation that there had been no involvement of the Senate in developing the agreement, which has “major” implications for the country’s finances as it commits the country to spending billions of extra Kenyan shillings.

“Who has appropriated that money? Where is the government going to get that money? Thousands of employees are going to be recruited to work under this arrangement, and then [in 2030], when the arrangement expires, they are supposed to transfer to the government,” Omtatah said.

An earlier draft of the agreement gave the US unfettered access to Kenya’s health data but, following an outcry from local organisations about the violation of patient confidentiality, the signed agreement has been amended to commit to data sharing in terms of Kenyan law:

The US-Kenya MOU tightens up confidentiality but gives the US a loophole in the event of a data breach.

The US-Kenya Data Sharing Agreement, which is an appendix to the main MOU, sets out the terms of access in more detail.

The court has instructed COFEK to serve all involved officials with the petition and court orders by December 17. The government has until January 16 to file its response. The case will return to court on February 12.

Civil society appeal to African leaders

Earlier this week, almost 50 civil society organisations published a letter calling on African heads of state and government to demand “equity and sovereignty” in their new bilateral health agreements with the United States.

Last week, the US signed bilateral agreements with Kenya, Rwanda, Liberia, Uganda and Lesotho as part of the revival of US health aid, including the US President’s Emergency Plan for AIDS Relief (PEPFAR), which was stopped abruptly when Donald Trump became US president in January, severely straining several African countries’ health systems.

In exchange, African countries have to commit to signing “specimen sharing agreements” to provide the US with “physical specimens and related data, including genetic sequence data, of detected pathogens with epidemic potential for either country within five days of detection”. 

Initially, the specimen-sharing was for 25 years, but in the agreements seen by Health Policy Watch, this has been trimmed down to between seven and 10 years. 

US, which pulled out of the World Health Organization (WHO) in January, appears to be trying to undermine the global talks on pathogen access and benefit-sharing (PABS) currently underway at the WHO.

The PABS system, the last outstanding issue in the Pandemic Agreement, will govern both how information about dangerous pathogens should be shared (the access part) and how countries that share this information should be rewarded (the benefits).

Countries that have signed MOUs have three months to present “implementation plans” to the US, and thus have the opportunity to negotiate better terms. However, civil society is completely shut out of these agreements, with the exception of “faith-based organisations” in Uganda that provide health services.

‘One-sided terms’

The letter urges African governments to “advance counterproposals grounded in national law, regional strategies, and public accountability, rather than accept one-sided terms”. 

“These agreements risk entrenching unequal power dynamics and compromising sovereignty,” said Aggrey Aluso, Executive Director of the Resilience Action Network Africa (RANA). 

“Africa has committed to building its own health sovereignty; no government should accept terms that hand long-term control of our data and pathogens to a foreign government – and its contractors – without clear, enforceable obligations that protect our people, uphold our laws, and strengthen public institutions,” Aluso added.

For example, Uganda’s MOU with the US demonstrates a lack of regard for the country’s sovereignty by declaring that the MOU’s implementation plan will be “an annex to Uganda’s national health budget and guide parliamentary appropriation”:

Uganda’s MOU with the US will become an annex to its health budget.

As with the Kenya-US MOU, the US commits $1,7 billion over five years while Uganda commits to increasing its domestic share of the items covered by $500 million over the same period.

Summary of Uganda and US financial obligations.

Meanwhile, Liberia will need to fund an additional 1,851 health workers, including 342 laboratory workers who may not normally have been a priority for the country, according to its MOU with the US.

By 2030, Liberia will shoulder almost its entire expenditure for commodities, including malaria and HIV diagnostics and countermeasures, at an annual cost of $10 million by 2030.

US-Liberia obligations for commodity payments.

‘Trade power and dignity’

“These deals ask countries to trade their power and a little of their dignity for less support than Trump took away early this year,” said Peter Maybarduk, director of Public Citizen’s Access to Medicines Program. 

“African nations have stood together to negotiate better access to medical tools ever since COVID’s deadly vaccine inequity. Trump would undermine even that principled stand. Each time we think we’ve seen the bottom, the Trump administration finds a way to dig a deeper, darker role for the United States in global health.”

Meanwhile, World Health Organization (WHO) Director General Dr Tedros Adhanom Ghebreyesus told a media briefing in Geneva on Thursday that the bilateral MOUs are agreements between two sovereign nations with their own national interests.

He added that the MOUs did not threaten the global pathogen-sharing agreement currently being negotiated at the WHO, as they would cover 50 countries maximum (according to the US) in comparison to the 194 WHO member stats.

“How many countries, maximum target, do they have? They say 50 countries. This cannot replace an agreement of an international nature. That means 194 countries. So the multilateral system, the common platform, fills almost every space. 

“We say solidarity is our best immunity, and this means all 194 countries should come to the table, if possible. Otherwise, the majority, probably 90% should achieve [a pathogen sharing arrangement] in order to make sure that the antigen come from all corners of the world. Because we never know where the next outbreak will come from.”

No link between Vaccines and Autism: WHO Director General Dr Tedros Adhanom Ghebreyesus discusses latest findings of the WHO Expert Committee.

A new WHO review has reaffirmed that childhood vaccines don’t cause autism, based on an examination of more than 25 years of studies scoping for possible linkages. 

There is no causal link, either, between vaccines containing preservatives such as thimerosal or aluminium and autism spectrum disorder (ASD), the review by the Global Advisory Committee on Vaccine Safety (GAVS), also found.

The findings, published Thursday, comes in the wake of a rash of statements by US Health and Human Services Secretary, Robert F. Kennedy Jr., reviving long dormant questions about a possible linkage. In March, Kennedy ordered the US Centres for Disease Prevention and Control (CDC) to conduct a review on the topic, which has not yet been completed. In November, he ordered the CDC to change language on its website reviving the long-debunked claims. 

The CDC website had previously stated that “studies have shown there is no link between receiving vaccines and developing autism spectrum disorder”.  Following the change, the site was updated to say that the claim “vaccines do not cause autism” is “not an evidence-based claim” – unleashing a wave of criticism from vaccine experts

New website text further says, “Scientific studies have not ruled out the possibility that infant vaccines contribute to the development of autism.”

However, another CDC page on thimerosal and vaccine safety, states that “research does not show any link between thimerosal in vaccines and autism, a neurodevelopmental disorder.”  It also points out, correctly, that the mercury-based preservative was removed from virtually all childhood vaccines decades ago.  Some flu vaccines still may contain thimerosal, also known as “thiomersal”.

The use of aluminium salts remains more common as adjuvants in vaccines such as those for hepatitis A, hepatitis B, diptheria, tetanus and pertussis (DTaP), and Human Papillomavirus (HPV).  But here, too, the WHO expert committee found no linkage between use of the adjuvant and autism.

Vaccines among the ‘most transformative’ inventions in history of humankind

Polio vaccination campaign in Pakistan. Polio vaccines never used either thimerosal our aluminium.

The WHO review was published Thursday simultaneous to a WHO press briefing by WHO Director General Dr Tedros Adhanom Ghebreyesus.  

“Over the past 25 years, under-five mortality has dropped by more than half, from 11 million deaths a year to 4.8 million, and vaccines are the major reason for that,” Tedros told the end-year press briefing, organized with the UN press corps organization ACANU.

“Vaccines are among the most powerful, transformative inventions in the history of humankind,” the WHO Director General added, noting that they “save lives from about 30 different diseases, including measles, cervical cancer, malaria and more.”

Like all medical products, vaccines can cause side effects. “But autism is not a side effect of vaccines,” Tedros affirmed. 

The WHO Expert Committee reviewed 31 new studies in multiple countries produced over the past 15 years examining associations between vaccines containing thiomersal and aluminium adjuvants and autism, as well as the association between vaccines and autism in general. It was the first such review since 2012.

“The committee concluded that the evidence shows no link between vaccines and autism, including vaccines containing aluminium or thiomersal,” Tedros declared.

“This is the fourth such review of the evidence, following similar reviews in 2002, 2004 and 2012. All reached the same conclusion: vaccines do not cause autism,” Tedros concluded.

He said that the new study reached the same findings as similar reviews in 2002, 2004 and 2012 – capturing evidence over some 25 years. 

Bucking national pressures

Health and Human Services Secretary Robert F Kennedy Jr. has revived long dormant questions about debunked links between vaccines and autism.

Since taking office earlier this year, Kennedy has not only revived debunked theories about a link between vaccines and autism, but he has also reduced US support for global polio vaccine efforts and lashed out at Gavi, the Vaccine Alliance about its DPT vaccination strategies. Just last week, recently a new CDC vaccine advisory committee packed with handpicked vaccine skeptics recommended against newborn vaccination against hepatitis B – another decision decried by experts. (See related story).

CDC Committee Delays Hepatitis B Vaccine for Newborns in Critical Guidelines Shift

In terms of any link between vaccines and autism, not only the WHO Vaccine Expert Committee, but numerous other advisory groups from around the world have come to the same conclusion regarding the lack of any linkage between vaccines and autism, WHO’s Katherine O’Brien, a senior vaccine expert, told the press briefing. 

“Not only when WHO has undertaken evidence reviews, but numerous advisory bodies around the world have consistently come to the same conclusions about the lack of risk of thimerosal or aluminium related to the autism questions,” O’Brien said. 

Katherine O’Brien, WHO head of Vaccines and Biologicals.

“And in particular, we develop our recommendations through external committees of experts who are drawn from around the world so that they can provide advice, and again, an independent review of the argument in order to assist the process of developing recommendations.” 

Asked whether WHO had been under pressure to changes its position due to the new US stance that the linkage between vaccines and autism remained an open question, Tedros said:  

“We disagree. We disagree respectfully, and we say no, because this is a science based organization, and science has to be respected.”

While he regrets the US decision to withdraw from WHO as of January, 2026, ressures from member states are nothing new Tedros added, saying, “I can give you many examples from the US, China, Russia and others.”   

Image Credits: UNICEF/Pakistan , HHS.