In the late 1990s, doctors treating sleeping sickness, a parasitic disease spread by tsetse flies that is almost always fatal without treatment, still relied on melarsoprol, an arsenic-based drug that killed roughly one patient in 20. One patient given melarsoprol in 2003 later recalled the injection “felt like fire” being injected into his veins, turning […] Continue reading ->
The US Food and Drug Administration (FDA) has approved the first generic version of lenacapavir, the highly effective twice-yearly injection to prevent HIV, developed by Dr Reddy’s Laboratories based in India. Dr Reddy’s was one of six pharmaceutical manufacturers that was granted a non-exclusive, royalty-free voluntary licensing agreement from Gilead, which developed lenacapavir. The agreement, […] Continue reading ->
Returning to lead the Global Fund, Mark Dybul argues that the future of global health lies with domestic health systems, not agency mergers in Geneva. Evoking the founding ambition of the early 2000s, the incoming executive director explains how the Accra Reset and US bilateral aid can align under unified national plans – and how […] Continue reading ->
A polio-free Africa is within reach, but only if we make it a priority. Ending the disease will not only protect our children, but it will also strengthen our health systems and safeguard us against future threats. The Ebola outbreak in Central Africa, with several cases of polio lurking in the shadows, remains an instructive […] Continue reading ->
The World Health Assembly chooses a new chief for the World Health Organization in May 2027. Before judging the candidates, assess the predecessors. Eight people have held the post over 78 years. Their varied track record offers pointers for selecting the future incumbent. Every five years, WHO rediscovers that its Director-Generalship is a political office […] Continue reading ->
ISRAELI-OCCUPIED WEST BANK – The oxygen mask slipped from three-month-old Ahmad Zaid’s face. He was in his father’s arms, in front of a closed Israeli military gate blocking the road between Deir Ammar refugee camp, northwest of Ramallah, where the family lives, and the city of Ramallah, with a hospital the family was desperate to […] Continue reading ->
The Medicines Patent Pool (MPP) has signed sublicense agreements with 11 manufacturers across multiple regions to expand access to generic baloxavir marboxil, a single-dose antiviral treatment for influenza that was originally developed by Swiss pharmaceutical company Roche. The announcement, made the night before last Friday’s UN High-Level Meeting on Pandemic Prevention, Preparedness and Response, reignited […] Continue reading ->
A new modelling study suggests that US Medicare “Most-Favored-Nation” policies on drug prices would cut Medicare spending on brand-name drugs, but potentially incentivize companies to increase prices or delay new drug launches elsewhere. Efforts to control the cost of government spending on drugs culminated in a Most-Favored-Nation (MFN) policy, a Trump administration initiative which ties […] Continue reading ->
After months of speculation, prospective candidates in the race to become the next Director-General of the World Health Organization (WHO) are now emerging. At the same time, member states have launched a process to review the global health architecture, with the aim of clarifying roles, strengthening coordination, and aligning financing more closely with national, regional, […] Continue reading ->
African scientists, institutions and communities are helping advance the development of new TB vaccines. Governments must now work together to prepare national systems, secure fair pricing and ensure scientific progress leads to timely and equitable access. When I visited the University of Cape Town Lung Institute and the South African Tuberculosis Vaccine Initiative (SATVI) in […] Continue reading ->